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KMID : 1035220190110020055
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Korean Journal of Neuromuscular Disorders
2019 Volume.11 No. 2 p.55 ~ p.58
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Severe Hyponatremia during Acyclovir Treatment in Shingles
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Shin Ji-Yong
Kim Mi-Yeon
Yoo Jeong-Rae
Kang Sa-Yoon
Oh Jung-Hwan
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Abstract
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Acyclovir is effective in treating the herpes virus infection, especially chickenpox and shingles. Hyponatremia caused by acyclovir has been rarely reported. We present a shingles patient with symptomatic hyponatremia that was presumably caused by acyclovir affecting the hypothalamus or posterior pituitary gland. This case demonstrates that the serum electrolyte levels should be checked regularly and careful observation of symptoms such as nausea, convulsions, or mentality change is necessary in patients treated with acyclovir.
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KEYWORD
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Acyclovir, Hyponatremia, Herpes zoster, Inappropriate ADH syndrome
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